USE OF HIGH WAVENUMBER RAMAN SPECTROSCOPY FOR MEAS

专利名称：USE OF HIGH WAVENUMBER RAMAN

SPECTROSCOPY FOR MEASURING TISSUE

发明人：PUPPELS, Gerwin, Jan,WOLTHUIS,

Rolf,KOLJENOVIC, Senada

申请号：EP03779036.7申请日：20031202公开号：EP1567852B1公开日：20070606

摘要：The invention is related to the instrument for measuring a Raman signal oftissue, the instrument comprising a laser, a signal detection unit for measuring the Ramansignal, and a fiber optic probe, wherein the fiber optic probe comprises one or moreoptical fibers for directing laser light onto the tissue and for collecting light that isscattered by the tissue and guiding the collected light away from the tissue towards thesignal detection unit, wherein the fiber or fibers for collecting light have substantially noRaman signal in one or more parts of the 2500-3700 cm-1 spectral region, and whereinthe detection unit records the Raman signal scattered by the tissue in said spectralregion. The invention enables ex vivo, in vitro and in vivo analysis and diagnosis of

atherosclerotic plaque and detection of tumor tissue with great advantages over currentstate-of-the-art technology.

申请人：RIVER DIAGNOSTICS B V

地址：NL

国籍：NL

代理机构：van Westenbrugge, Andries

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