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Indazoles, benzothiazoles, benzoisothiazoles, benz

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专利名称:Indazoles, benzothiazoles,

benzoisothiazoles, benzisoxazoles, andpreparation and use thereof

发明人:Wenge Xie,Brian Herbert,Richard A.

Schumacher,Truc Minh Nguyen,JianguoMa,Carla Maria Gauss,Ashok Tehim

申请号:US13165370申请日:20110621公开号:US08486937B2公开日:20130716

摘要:The present invention relates generally to the field of ligands for nicotinicacetylcholine receptors (nACh receptors), activation of nACh receptors, and thetreatment of disease conditions associated with defective or malfunctioning nicotinicacetylcholine receptors, especially of the brain. Further, this invention relates to novelcompounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nAChreceptor subtype, methods of preparing such compounds, compositions containing suchcompounds, and methods of use thereof.

申请人:Wenge Xie,Brian Herbert,Richard A. Schumacher,Truc Minh Nguyen,JianguoMa,Carla Maria Gauss,Ashok Tehim

地址:Mahwah NJ US,Stockholm NJ US,Monroe NY US,New York NY US,Montvale NYUS,New York NY US,Ridgewood NJ US

国籍:US,US,US,US,US,US,US

代理机构:Millen, White, Zelano & Branigan, P.C.

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