专利名称：Cell culture methods发明人：Ben Yahia, Bassem,Malphettes,
Laetitia,Kochanowski, Nadine,Renner,Gill,Durran, Sandrine,Yates, Andrew Jeffrey
申请号：AU2018276376申请日：20180529公开号：AU2018276376A1公开日：20191212
摘要：The present invention relates to the use of limited amounts of cysteine andtryptophan in the cell culture medium during production of recombinant proteins, and inparticular antibodies. Proteins and antibodies produced under such controlled conditionsexhibit reduced heterogeneity, in particular reduced charge variants heterogeneity.
申请人：UCB Biopharma SPRL
代理人：Griffith Hack
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