Protective antigen of group a streptococci

专利名称：Protective antigen of group a streptococci发明人：James B. Dale申请号：US113439申请日：20060130

公开号：US20060246083A1公开日：20061102

摘要：The present invention provides the discovery of a new protective antigen(herein designated Spa) which has been identified and isolated from Spa is a surfaceantigen distinct from M protein which evokes opsonic antibodies that are protectiveagainst multiple serotypes of The invention further provides isolated Spa polypeptides,proteins, peptides, and antibodies against the same, as well as nucleic acids encoding Spapolypeptide and peptide antigens. Also provided are methods for identification andisolation of a Spa polypeptide, therapeutic compositions comprised of Spa antigens orantibodies and methods of their use in protecting an animal against a infection.

申请人：James B. Dale

地址：Memphis TN US

国籍：US

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